Uncertainty evaluation of parameters used in LC-MS/MS system suitability for the determination of pesticide residues |
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| Miliadis, G., Tsiantas, P., Paraskevaidi, K., Siragakis, G. |
- Abstract:
- Parameters used to assess LC-MS/MS system suitability for the determination of the concentration of pesticide residues in food are the retention time, the ion ratio, the signal to noise ratio and the slope of the calibration line.
The EU tolerance values of the first two of these parameters have changed more than one time during the last years in the SANTE Document (last edition 11945/2015), they are differentiated from the respective tolerances mentioned in the Commission Decision 657/2002, and have been subject of debate.
In the present study system suitability parameters of LC-MS/MS were evaluated under the same LC- MS/MS conditions at concentration 0.01µg/mL, over 28 months’ period. Six representative compounds were used for this purpose and the respective control charts were constructed. The uncertainty values of these parameters were evaluated and compared to respective values of the literature. - Download:
- IMEKO-TC23-2017-013.pdf
- DOI:
- -
- Event details
- IMEKO TC:
- TC23
- Event name:
- 3rd IMEKOFOODS Conference
- Title:
Metrology Promoting Standardization and Harmonization in Food and Nutrition
- Place:
- Thessaloniki, GREECE
- Time:
- 01 October 2017 - 04 October 2017