IN VIVO ASSESSMENT OF SKIN IMPEDANCE RECOVERY AFTER LOW-VOLTAGE PULSES ELECTROPORATION |
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| Pasquale Arpaia, Fabrizio Clemente, Carlo Manna |
- Abstract:
- The aim of this work is to measure the skin impedance recovery after electroporation by using low-voltage pulse protocol on human subject. Before and after electroporation, based on square wave pulses of 20-50 V, 5 μs, for 15-20 minutes, Electrical Impedance Spectroscopy (EIS) measurements has been performed, in the frequency range 0.5-10 kHz. Preliminary experimental results show a significant decrease in skin impedance amplitude after treatment. This result turns out to be useful in a measurement procedure aimed at determining the amount of drug actually transferred in electroporation-based therapy.
- Download:
- IMEKO-TC4-2008-179.pdf
- DOI:
- -
- Event details
- IMEKO TC:
- TC4
- Event name:
- Exploring New Frontiers of Instrumentation and Methods for Electrical and Electronic Measurements
- Title:
- XVIth IMEKO TC4 International Symposium on Electrical Measurements and Instrumentation (together with 13th IMEKO TC4 Workshop on ADC Modelling and Testing)
- Place:
- Florence, ITALY
- Time:
- 22 September 2008 - 24 September 2008